Propargyl-PEG12-bromide

Modify Date: 2025-08-26 19:57:09

Propargyl-PEG12-bromide Structure
Propargyl-PEG12-bromide structure
Common Name Propargyl-PEG12-bromide
CAS Number 2410937-34-5 Molecular Weight 691.64
Density N/A Boiling Point N/A
Molecular Formula C29H55BrO13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG12-bromide


Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG12-bromide

 Propargyl-PEG12-bromide Biological Activity

Description Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C29H55BrO13
Molecular Weight 691.64
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