2410937-34-5

2410937-34-5 structure

2410937-34-5 structure

Name: Propargyl-PEG12-bromide
Chemical Name: Propargyl-PEG12-bromide
CAS Number: 2410937-34-5
Molecular Formula: C₂₉H₅₅BrO₁₃
Molecular Weight: 691.64
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:34:37
Modify Date: 2024-01-09 12:06:36
Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG12-bromide

Description	Propargyl-PEG12-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₉H₅₅BrO₁₃
Molecular Weight	691.64