1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate

Modify Date: 2025-10-01 12:34:26

1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate structure	Common Name	1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate
	CAS Number	843666-34-2	Molecular Weight	467.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₅NO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate

Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-C16-NHS ester
Synonym	More Synonyms

Description	Boc-C16-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₅NO₆
Molecular Weight	467.64
InChIKey	JTOVMMPSILRQQJ-UHFFFAOYSA-N
SMILES	CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O

MFCD29923003

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.