| Name | Acid-PEG4-t-butyl ester |
|---|---|
| Synonyms |
MFCD28096679
Bis(2-methyl-2-propanyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(1,1-dimethylethyl) ester |
| Description | Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.9±35.0 °C at 760 mmHg |
| Molecular Formula | C16H30O8 |
| Molecular Weight | 406.511 |
| Flash Point | 191.1±26.0 °C |
| Exact Mass | 406.256653 |
| LogP | 1.84 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.450 |
| Storage condition | 2-8°C |