Folate-PEG2-amine

Modify Date: 2024-01-31 15:26:01

Folate-PEG2-amine Structure
Folate-PEG2-amine structure
Common Name Folate-PEG2-amine
CAS Number 1099829-15-8 Molecular Weight 571.59
Density N/A Boiling Point N/A
Molecular Formula C25H33N9O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Folate-PEG2-amine


Folate-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Folate-PEG2-amine

 Folate-PEG2-amine Biological Activity

Description Folate-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C25H33N9O7
Molecular Weight 571.59