Mal-PEG2-amine TFA

Modify Date: 2024-01-08 13:30:08

Mal-PEG2-amine TFA Structure
Mal-PEG2-amine TFA structure
Common Name Mal-PEG2-amine TFA
CAS Number 660843-22-1 Molecular Weight 228.25
Density N/A Boiling Point N/A
Molecular Formula C10H16N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG2-amine TFA


Mal-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG2-NH2

 Mal-PEG2-amine TFA Biological Activity

Description Mal-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H16N2O4
Molecular Weight 228.25
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