2250216-96-5

2250216-96-5 structure

2250216-96-5 structure

Name: DBCO-PEG2-amine
Chemical Name: DBCO-PEG2-amine
CAS Number: 2250216-96-5
Molecular Formula: C₂₅H₂₉N₃O₄
Molecular Weight: 435.52
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:27:49
Modify Date: 2024-01-13 16:16:49
DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG2-amine

Description	DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₅H₂₉N₃O₄
Molecular Weight	435.52