DBCO-PEG2-amine

Modify Date: 2024-01-13 16:16:49

DBCO-PEG2-amine Structure
DBCO-PEG2-amine structure
Common Name DBCO-PEG2-amine
CAS Number 2250216-96-5 Molecular Weight 435.52
Density N/A Boiling Point N/A
Molecular Formula C25H29N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG2-amine


DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG2-amine

 DBCO-PEG2-amine Biological Activity

Description DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H29N3O4
Molecular Weight 435.52
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