Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].
N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Amine-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
DBCO-Biotin is a Click Chemistry intermidate used for antibody-drug conjugates.
PROTAC Linker 31 is a PROTAC linker, which refers to the Alkyl-Chain composition. PROTAC Linker 31 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
1,1,1-Trifluoroethyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fmoc-NH-PEG12-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523)[1].
NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bis-PEG3-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Br-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG3-CH2-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.
Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
m-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-NH-C4-acid is a PROTAC linker, which belongs to a Alkyl/ether linker. Boc-NH-C4-acid can be used in the synthesis of the compound PROTAC1, and specifically degrades EED, EZH2, and SUZ12 in the PRC2 Complex.
Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hexaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PEG5-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].