1807534-85-5

1807534-85-5 structure

Name: Fmoc-PEG2-NHS ester
Chemical Name: Fmoc-PEG2-C2-NHS ester
CAS Number: 1807534-85-5
Molecular Formula: C₂₆H₂₈N₂O₈
Molecular Weight: 496.51
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-10 20:12:38
Modify Date: 2024-01-02 09:25:34
Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fmoc-PEG2-C2-NHS ester

Description	Fmoc-PEG2-CH2CH2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562