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2241669-16-7

2241669-16-7 structure
2241669-16-7 structure
  • Name: NH2-PEG5-C6-Cl hydrochloride
  • Chemical Name: NH2-PEG5-C6-Cl hydrochloride
  • CAS Number: 2241669-16-7
  • Molecular Formula: C16H35Cl2NO5
  • Molecular Weight: 392.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 20:03:46
  • Modify Date: 2024-01-26 17:51:28
  • NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH2-PEG5-C6-Cl hydrochloride
Description NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H35Cl2NO5
Molecular Weight 392.36