NH2-PEG5-C6-Cl hydrochloride

Modify Date: 2024-01-26 17:51:28

NH2-PEG5-C6-Cl hydrochloride Structure
NH2-PEG5-C6-Cl hydrochloride structure
Common Name NH2-PEG5-C6-Cl hydrochloride
CAS Number 2241669-16-7 Molecular Weight 392.36
Density N/A Boiling Point N/A
Molecular Formula C16H35Cl2NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG5-C6-Cl hydrochloride


NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH2-PEG5-C6-Cl hydrochloride

 NH2-PEG5-C6-Cl hydrochloride Biological Activity

Description NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H35Cl2NO5
Molecular Weight 392.36
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