NH2-PEG2-C6-Cl

Modify Date: 2024-01-02 11:47:12

NH2-PEG2-C6-Cl Structure
NH2-PEG2-C6-Cl structure
Common Name NH2-PEG2-C6-Cl
CAS Number 744203-60-9 Molecular Weight 223.74
Density N/A Boiling Point N/A
Molecular Formula C10H22ClNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NH2-PEG2-C6-Cl


NH2-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name NH2-PEG2-C6-Cl

 NH2-PEG2-C6-Cl Biological Activity

Description NH2-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H22ClNO2
Molecular Weight 223.74