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744203-60-9

744203-60-9 structure
744203-60-9 structure
  • Name: NH2-PEG2-C6-Cl
  • Chemical Name: NH2-PEG2-C6-Cl
  • CAS Number: 744203-60-9
  • Molecular Formula: C10H22ClNO2
  • Molecular Weight: 223.74
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 13:17:09
  • Modify Date: 2024-01-02 11:47:12
  • NH2-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Name NH2-PEG2-C6-Cl
Description NH2-PEG2-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Molecular Formula C10H22ClNO2
Molecular Weight 223.74

Chemsrc provides CAS#:744203-60-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 744203-60-9 | Chemsrc address: https://www.chemsrc.com/en/baike/1571642.html

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