Bromo-PEG3-alcohol

Modify Date: 2024-01-02 12:07:49

Bromo-PEG3-alcohol Structure
Bromo-PEG3-alcohol structure
Common Name Bromo-PEG3-alcohol
CAS Number 57641-67-5 Molecular Weight 213.07000
Density 1.411±0.06 g/cm3 Boiling Point 276.3±20.0 °C
Molecular Formula C6H13BrO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG3-alcohol


Br-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-(2-bromoethoxy)ethoxy]ethan-1-ol
Synonym More Synonyms

 Bromo-PEG3-alcohol Biological Activity

Description Br-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.411±0.06 g/cm3
Boiling Point 276.3±20.0 °C
Molecular Formula C6H13BrO3
Molecular Weight 213.07000
Exact Mass 212.00500
PSA 38.69000
LogP 0.40680

 Safety Information

Hazard Codes T+

 Synonyms

2-[2-(2-Brom-aethoxy)-aethoxy]-aethanol
2-(2-(2-bromoethoxy)ethoxy)ethanol
Diaethylenglykol-mono-(2-brom-aethylaether)
Bromo-PEG3-alcohol
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