1148026-98-5
1148026-98-5 structure
- Name: Bromo-PEG3-phosphonic acid diethyl ester
- Chemical Name: Diethyl (2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethyl)phosphonate
- CAS Number: 1148026-98-5
- Molecular Formula: C12H26BrO6P
- Molecular Weight: 377.209
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-13 19:04:44
- Modify Date: 2024-01-02 19:54:22
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Bromo-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Diethyl (2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethyl)phosphonate |
|---|---|
| Synonyms |
Diethyl (2-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}ethyl)phosphonate
Phosphonic acid, P-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl]-, diethyl ester MFCD11982880 |
| Description | Bromo-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 426.5±35.0 °C at 760 mmHg |
| Molecular Formula | C12H26BrO6P |
| Molecular Weight | 377.209 |
| Flash Point | 211.7±25.9 °C |
| Exact Mass | 376.065033 |
| LogP | -0.02 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.460 |