Bromo-PEG3-CH2CO2tBu

Modify Date: 2024-01-09 15:06:59

Bromo-PEG3-CH2CO2tBu Structure
Bromo-PEG3-CH2CO2tBu structure
Common Name Bromo-PEG3-CH2CO2tBu
CAS Number 2100306-71-4 Molecular Weight 327.21
Density N/A Boiling Point N/A
Molecular Formula C12H23BrO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG3-CH2CO2tBu


Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG3-CH2-Boc
Synonym More Synonyms

 Bromo-PEG3-CH2CO2tBu Biological Activity

Description Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H23BrO5
Molecular Weight 327.21

 Synonyms

MFCD30723231