882518-89-0
882518-89-0 structure
- Name: Tos-PEG2-CH2-Boc
- Chemical Name: Tos-PEG3-CH2CO2tBu
- CAS Number: 882518-89-0
- Molecular Formula: C17H26O7S
- Molecular Weight: 374.449
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-06 06:55:38
- Modify Date: 2024-01-10 10:42:34
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Tos-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Tos-PEG3-CH2CO2tBu |
|---|---|
| Synonyms |
Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl [2-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]acetate MFCD27977515 |
| Description | Tos-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 484.0±35.0 °C at 760 mmHg |
| Molecular Formula | C17H26O7S |
| Molecular Weight | 374.449 |
| Flash Point | 246.5±25.9 °C |
| Exact Mass | 374.139923 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.499 |
| Hazard Codes | Xi |
|---|