2378049-28-4

2378049-28-4 structure

2378049-28-4 structure

Name: Hydroxy-PEG7-CH2-Boc
Chemical Name: Hydroxy-PEG7-CH2-Boc
CAS Number: 2378049-28-4
Molecular Formula: C₂₀H₄₀O₁₀
Molecular Weight: 440.53
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:49:51
Modify Date: 2024-01-10 11:20:00
Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Hydroxy-PEG7-CH2-Boc

Description	Hydroxy-PEG7-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₀H₄₀O₁₀
Molecular Weight	440.53