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2100306-53-2

2100306-53-2 structure
2100306-53-2 structure
  • Name: Bis-PEG4-t-butyl ester
  • Chemical Name: Bis-PEG4-t-butyl ester
  • CAS Number: 2100306-53-2
  • Molecular Formula: C20H38O8
  • Molecular Weight: 406.51
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 21:38:28
  • Modify Date: 2024-01-09 20:07:28
  • Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-PEG4-t-butyl ester
Description Bis-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H38O8
Molecular Weight 406.51