1343472-07-0

1343472-07-0 structure

Name: Azido-PEG8-CH2CO2H
Chemical Name: N3-PEG8-CH2COOH
CAS Number: 1343472-07-0
Molecular Formula: C₁₈H₃₅N₃O₁₀
Molecular Weight: 453.485
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-06 20:21:17
Modify Date: 2024-01-22 10:05:12
N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	N3-PEG8-CH2COOH
Synonyms	AZIDE-PEG8-CH2COOH

Description	N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Steinmetz NF, et al. Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors. Small. 2011 Jun 20;7(12):1664-72.