Amino-PEG10-amine

Modify Date: 2024-01-14 18:43:25

Amino-PEG10-amine Structure
Amino-PEG10-amine structure
Common Name Amino-PEG10-amine
CAS Number 928292-69-7 Molecular Weight 500.62400
Density 1.082±0.06 g/cm3 (20 °C, 760 mmHg) Boiling Point 560.0±45.0 °C (760 mmHg)
Molecular Formula C22H48N2O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG10-amine


Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].

 Names

Name 3,6,9,12,15,18,21,24,27,30-Decaoxadotriacontane-1,32-diamine
Synonym More Synonyms

 Amino-PEG10-amine Biological Activity

Description Amino-PEG10-amine, a PEG-based PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].
Related Catalog
Target

PEGs

References

[1]. Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.

 Chemical & Physical Properties

Density 1.082±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point 560.0±45.0 °C (760 mmHg)
Molecular Formula C22H48N2O10
Molecular Weight 500.62400
Exact Mass 500.33100
PSA 144.34000
LogP 0.47040
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi

 Synonyms

h2n-peg10-ch2ch2nh2