Amino-PEG7-amine

Modify Date: 2025-08-25 10:19:42

Amino-PEG7-amine Structure
Amino-PEG7-amine structure
Common Name Amino-PEG7-amine
CAS Number 332941-25-0 Molecular Weight 368.46600
Density N/A Boiling Point N/A
Molecular Formula C16H36N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG7-amine


Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name O,O′-Bis(2-aminoethyl)hexaethylene Glycol
Synonym More Synonyms

 Amino-PEG7-amine Biological Activity

Description Amino-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H36N2O7
Molecular Weight 368.46600
Exact Mass 368.25200
PSA 116.65000
LogP 0.42060
InChIKey MWECBIRKDAZDRL-UHFFFAOYSA-N
SMILES NCCOCCOCCOCCOCCOCCOCCOCCN
Storage condition 2-8°C

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
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