76927-70-3

76927-70-3 structure

Name: Amino-PEG6-amine
Chemical Name: peoda7
CAS Number: 76927-70-3
Molecular Formula: C₁₄H₃₂N₂O₆
Molecular Weight: 324.41400
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-01-16 12:37:52
Modify Date: 2024-01-05 16:19:58
Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.

Name	peoda7
Synonyms	O,O'-bis(2-aminoethyl)pentaethylene glycol 1,20-Diamino-3,6,9,12,15,18-hexaoxaeicosane 2-{2-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethylamine

Description	Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.