Amino-PEG2-NH-Boc
Amino-PEG2-NH-Boc structure
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Common Name | Amino-PEG2-NH-Boc | ||
|---|---|---|---|---|
| CAS Number | 127828-22-2 | Molecular Weight | 204.26700 | |
| Density | 1.024g/cm3 | Boiling Point | 321.128ºC at 760 mmHg | |
| Molecular Formula | C9H20N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 148.013ºC | |
Use of Amino-PEG2-NH-BocAmino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
| Name | tert-butyl N-[2-(2-aminoethoxy)ethyl]carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.024g/cm3 |
|---|---|
| Boiling Point | 321.128ºC at 760 mmHg |
| Molecular Formula | C9H20N2O3 |
| Molecular Weight | 204.26700 |
| Flash Point | 148.013ºC |
| Exact Mass | 204.14700 |
| PSA | 77.07000 |
| LogP | 1.39110 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.457 |
| Water Solubility | Soluble (53 g/L) (25 ºC) |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2924199090 |
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~79%
Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: EP1745802 A1, ; Page/Page column 17 ; |
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~82%
Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: Journal of Organic Chemistry, , vol. 72, # 7 p. 2289 - 2296 |
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~99%
Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: Tetrahedron Letters, , vol. 47, # 17 p. 2915 - 2919 |
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Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: EP2123283 A1, ; Page/Page column 15 ; |
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Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: US2011/269965 A1, ; |
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Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: US2011/269965 A1, ; |
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Amino-PEG2-NH-Boc CAS#:127828-22-2 |
| Literature: US2011/269965 A1, ; |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| AmbotzPEG1067 |
| 1-t-butoxycarbonylamino-3-oxa-pentan-5-amine |
| N-Boc-2-(2-amino-ethoxy)-ethylamine |
| tert-butyl 2-(2-aminoethoxy)ethylcarbamate |
| N-(tert-butyloxycarbonyl)-2,2'-oxybis(ethylamine) |
| 5-(tert-butyloxycarbonylamino)-3-oxa-pentyl amine |
| N-t-butoxycarbonyl-3-oxa-1,5-pentanediamine |
| tert-Butyl [2-(2-aminoethoxy)ethyl]carbamate |
| BOCNH-PEG1-CH2CH2NH2 |