Boc-NH-PEG2-NH-Boc

Modify Date: 2024-01-02 23:54:48

Boc-NH-PEG2-NH-Boc Structure
Boc-NH-PEG2-NH-Boc structure
Common Name Boc-NH-PEG2-NH-Boc
CAS Number 475591-59-4 Molecular Weight 348.43500
Density N/A Boiling Point N/A
Molecular Formula C16H32N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-NH-PEG2-NH-Boc


Boc-NH-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,8-di-(tert-butoxycarbonylamino)-3,6-dioxaoctane
Synonym More Synonyms

 Boc-NH-PEG2-NH-Boc Biological Activity

Description Boc-NH-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H32N2O6
Molecular Weight 348.43500
Exact Mass 348.22600
PSA 95.12000
LogP 2.85080

 Synonyms

MFCD08067562