Azido-PEG7-amine structure
|
Common Name | Azido-PEG7-amine | ||
|---|---|---|---|---|
| CAS Number | 1333154-77-0 | Molecular Weight | 394.46400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H34N4O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Azido-PEG7-amineAzido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | α-amino,ω-azido,α,ω-dideoxy-octaethyleneglycol |
|---|---|
| Synonym | More Synonyms |
| Description | Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1. |
| Molecular Formula | C16H34N4O7 |
|---|---|
| Molecular Weight | 394.46400 |
| Exact Mass | 394.24300 |
| PSA | 140.38000 |
| LogP | 0.52466 |
| InChIKey | VZKXLNRXAFTBOW-UHFFFAOYSA-N |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCN |
| α-(2-aminoethyl)-ω-(2-azidoethoxy)hexa(oxyethylene) |