Azido-PEG7-azide

Modify Date: 2024-01-09 19:38:19

Azido-PEG7-azide Structure
Azido-PEG7-azide structure
Common Name Azido-PEG7-azide
CAS Number 225523-86-4 Molecular Weight 420.461
Density N/A Boiling Point N/A
Molecular Formula C16H32N6O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG7-azide


Azido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1,23-Diazido-3,6,9,12,15,18,21-heptaoxatricosane
Synonym More Synonyms

 Azido-PEG7-azide Biological Activity

Description Azido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H32N6O7
Molecular Weight 420.461
Exact Mass 420.233246
LogP -1.66

 Synonyms

3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-diazido-
1,23-Diazido-3,6,9,12,15,18,21-heptaoxatricosane
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