1818294-30-2

1818294-30-2 structure

Name: Trityl-PEG8-azide
Chemical Name: Trityl-PEG7-Azide
CAS Number: 1818294-30-2
Molecular Formula: C₃₅H₄₇N₃O₈
Molecular Weight: 637.763
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-17 07:05:32
Modify Date: 2024-01-09 17:46:08
Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Trityl-PEG7-Azide
Synonyms	25-Azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosane MFCD22683296 2,5,8,11,14,17,20,23-Octaoxapentacosane, 25-azido-1,1,1-triphenyl-

Description	Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562