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100688-48-0

100688-48-0 structure
100688-48-0 structure
  • Name: m-PEG3-CH2-alcohol
  • Chemical Name: 3-[2-(2-methoxyethoxy)ethoxy]propan-1-ol
  • CAS Number: 100688-48-0
  • Molecular Formula: C8H18O4
  • Molecular Weight: 178.22600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-06-09 02:40:04
  • Modify Date: 2024-01-09 12:08:23
  • m-PEG3-CH2-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name 3-[2-(2-methoxyethoxy)ethoxy]propan-1-ol
Synonyms 1-Propanol,3-[2-(2-methoxyethoxy)ethoxy]
Description m-PEG3-CH2-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

Molecular Formula C8H18O4
Molecular Weight 178.22600
Exact Mass 178.12100
PSA 47.92000
LogP 0.04840
Hazard Codes Xi