Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

MASM7

MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins[1].

  • CAS Number: 920868-45-7
  • MF: C22H23N5O2S2
  • MW: 453.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12(S)-HETE D8

12(S)-HETE D8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. It is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE D8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.

  • CAS Number: 84807-90-9
  • MF: C20H24D8O3
  • MW: 328.51600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Prednisolone Farnesylate

PNF21 is a new transdermal corticosteroid with anti-inflammatory activity.

  • CAS Number: 118244-44-3
  • MF: C36H50O6
  • MW: 578.77900
  • Catalog: Inflammation/Immunology
  • Density: 1.15g/cm3
  • Boiling Point: 712.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 217.5ºC

Eclalbasaponin IV

Eclalbasaponin IV is a triterpenoid that can be isolate from the aerial parts of Eclipta prostrata. Eclalbasaponin IV shows antitumor activity in human ovarian cancer cells[1].

  • CAS Number: 158511-61-6
  • MF: C42H68O14
  • MW: 796.98
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-m-Tyrosine

L-m-Tyrosine is an unnatural amino acid, that has potential in the research of Parkinsons disease, Alzheimers disease, and arthritis[1].

  • CAS Number: 587-33-7
  • MF: C9H11NO3
  • MW: 181.189
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 387.2±32.0 °C at 760 mmHg
  • Melting Point: 260-270ºC
  • Flash Point: 188.0±25.1 °C

24-Epicastasterone

24-Epicastasterone (24-epi-Castasterone), a brassinosteroid, is a nature product that could be isolated from Hydrodictyon reticulatwn[1].

  • CAS Number: 72050-71-6
  • MF: C28H47O5
  • MW: 463.67000
  • Catalog: Others
  • Density: 1.127g/cm3
  • Boiling Point: 598.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 329.9ºC

4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester

Dabcyl acid, SE is the amino-reactive form of Dabcyl acid (DABCYL), and widely used to prepare a variety of FRET-based probes that contain DABCYL.

  • CAS Number: 146998-31-4
  • MF: C19H18N4O4
  • MW: 366.371
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 550.7±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.9±32.9 °C

GK921

GK921 is a transglutaminase 2 (TGase) inhibitor with an IC50 of 7.71 μM for human recombinant TGase 2.

  • CAS Number: 1025015-40-0
  • MF: C21H20N4O
  • MW: 344.41000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydroxygenkwanin

Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect[1][2].

  • CAS Number: 20243-59-8
  • MF: C16H12O6
  • MW: 300.263
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 602.7±55.0 °C at 760 mmHg
  • Melting Point: 225-227ºC
  • Flash Point: 230.6±25.0 °C

8-Hydroxycoumarin

8-Hydroxycoumarin is an intermediate in the microbial transformation of quinolone[1].

  • CAS Number: 2442-31-1
  • MF: C9H6O3
  • MW: 162.14200
  • Catalog: Infection
  • Density: 1.403g/cm3
  • Boiling Point: 361.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 170.3ºC

beta-Casein phosphopeptide

beta-Casein phosphopeptide is a biological active peptide. (Bovine ?-Casein, monophosphopeptide (phospho-Serine) can be used for characterization of affinity purified phosphorylated peptides in liquid chromatography and for the analysis or detection of phosphorylated peptides in mass spectrometry.)

  • CAS Number: 183582-09-4
  • MF: C81H125N22O39P
  • MW: 2061.96
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Berberrubine

Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model[1].

  • CAS Number: 15401-69-1
  • MF: C19H16ClNO4
  • MW: 357.788
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 245℃ (DEC.)
  • Flash Point: N/A

8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt

ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage[1].

  • CAS Number: 5398-34-5
  • MF: C10H7NNa2O9S3
  • MW: 427.33800
  • Catalog: Others
  • Density: 1.974g/cm3
  • Boiling Point: N/A
  • Melting Point: 138 °C (dec.)(lit.)
  • Flash Point: N/A

Dalnicastobart

Dalnicastobart (LVGN-7409) is a human IgG1κ antibody targeting CD40/TNFRSF5[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fibulostatin 6.2

Fibulostatin 6.2 is an anti-angiogenic peptide that can inhibit migration of human umbilical vein endothelial cells in vitro[1].

  • CAS Number: 945373-84-2
  • MF: C76H126N30O26S2
  • MW: 1940.13
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

blumeatin

Blumeatin, isolated from Blumea balsamifera DC, could protect liver against injury induced by CCl4 and thioacetamide (TAA)[1].

  • CAS Number: 118024-26-3
  • MF: C16H14O6
  • MW: 302.279
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 603.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 229.7±25.0 °C

Propargylcholine (bromide)

Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells[1][2].

  • CAS Number: 111755-76-1
  • MF: C7H14BrNO
  • MW: 208.096
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TNF-α (46-65), human

TNF-α (46-65), human is a peptide of TNF-α.

  • CAS Number: 144796-72-5
  • MF: C110H172N24O30
  • MW: 2310.69000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FGL peptide

FGL peptide is a biologically active peptide.

  • CAS Number: 499993-62-3
  • MF: C71H116N20O25
  • MW: 1649.80
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-epi-Deoxyloganic acid

8-Epideoxyloganic acid (7-Deoxy-8-epiloganic acid), an iridoid glucoside, can be found in Incarvillea delavayi. 8-Epideoxyloganic acid exhibits weak antinociceptive activity[1].

  • CAS Number: 88668-99-9
  • MF: C16H24O9
  • MW: 360.356
  • Catalog: Neurological Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 597.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 217.9±23.6 °C

Alpinoid D

Alpinoid D, a diarylheptanoid, can be isolated from the MeOH extract from the rhizomes of Alpinia officinarum Hance. Alpinoid D shows cytotoxic effect against IMR-32 human neuroblastoma cell line[1].

  • CAS Number: 1041740-13-9
  • MF: C20H20O3
  • MW: 308.371
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 438.2±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.8±27.3 °C

Re 80

Re 80 is an anti-angiogenic agent and is a synthetic retinoid[1].

  • CAS Number: 116193-60-3
  • MF: C24H26O5
  • MW: 394.46000
  • Catalog: Inflammation/Immunology
  • Density: 1.212g/cm3
  • Boiling Point: 613.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 338.9ºC

Lasofoxifene-d4

Lasofoxifene-d4 is the deuterium labeled Lasofoxifene. Lasofoxifene is a non-steroidal selective estrogen receptor modulator (SERM)[1][2].

  • CAS Number: 1126626-61-6
  • MF: C28H27D4NO2
  • MW: 417.58
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

colupulone

β-Acids colupulone is the bitter substance. β-Acids colupulone can be isolated from hops[1].

  • CAS Number: 468-27-9
  • MF: C25H36O4
  • MW: 400.55
  • Catalog: Others
  • Density: 1.053g/cm3
  • Boiling Point: 573.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 314.9ºC

1,2,4-Triazolylsodium

1,2,4-Triazole (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].

  • CAS Number: 41253-21-8
  • MF: C2H3N3Na
  • MW: 92.06
  • Catalog: Infection
  • Density: 1.255
  • Boiling Point: 260ºC at 760 mmHg
  • Melting Point: 295 °C (dec.)(lit.)
  • Flash Point: 139.1ºC

N-Methylpiperazine--d8

1-Methylpiperazine-2,2,3,3,5,5,6,6-d8 is the deuterium labeled 1-Methylpiperazine-2,2,3,3,5,5,6,6-d8[1].

  • CAS Number: 917358-65-7
  • MF: C5H4D8N2
  • MW: 108.21100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 216-218°C
  • Flash Point: N/A

1-Bromo-4-fluorobenzene-d4

1-Bromo-4-fluorobenzene-d4 is the deuterium labeled 1-Bromo-4-fluorobenzene[1].

  • CAS Number: 50592-31-9
  • MF: C6BrD4F
  • MW: 179.02300
  • Catalog: Others
  • Density: 1.629 g/mL at 25ºC
  • Boiling Point: 150ºC(lit.)
  • Melting Point: -16ºC(lit.)
  • Flash Point: 60ºC

CSNK1-IN-1

CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].

  • CAS Number: 2468784-55-4
  • MF: C29H26F3N5O2
  • MW: 533.54
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2-Chloropyridin-4-yl)methanamine hydrochloride

LOXL2-IN-1 hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.

  • CAS Number: 916210-98-5
  • MF: C6H8Cl2N2
  • MW: 179.047
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

rac-Clopidogrel Amide-d4

rac-Clopidogrel Amide-d4 is the deuterium labeled rac-Clopidogrel Amide[1].

  • CAS Number: 1219423-91-2
  • MF: C15H15ClN2OS
  • MW: 306.8104
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >53°C (dec.)
  • Flash Point: N/A