CSNK1-IN-1

Modify Date: 2025-08-25 19:42:45

CSNK1-IN-1 Structure
CSNK1-IN-1 structure
Common Name CSNK1-IN-1
CAS Number 2468784-55-4 Molecular Weight 533.54
Density N/A Boiling Point N/A
Molecular Formula C29H26F3N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CSNK1-IN-1


CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].

 Names

Name CSNK1-IN-1

 CSNK1-IN-1 Biological Activity

Description CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].
Related Catalog
Target

IC50: 21 μM (CSNK1A1 kinase)[1]

In Vitro CSNK1-IN-1 对 CSNK1A1, CSNK1D 和 CSNK1A1 (高 ATP) 具有抑制活性,IC50 值分别为 21 μM, 29.7 μM 和 1.5 nM[1]。< br / >CSNK1-IN-1 对野生型 EGFR 激酶表现出低抑制作用,其 IC50 值为 >20 nM[1]。
References

[1]. Volker Schulze, et al. 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

 Chemical & Physical Properties

Molecular Formula C29H26F3N5O2
Molecular Weight 533.54
InChIKey IKATWWUGCJFQJV-OAQYLSRUSA-N
SMILES CN1CCc2[nH]c(-c3ccnc(NC(=O)C(CC(F)F)c4ccc(F)cc4)c3)c(Nc3ccccc3)c2C1=O
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