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2468784-55-4

2468784-55-4 structure

2468784-55-4 structure

Name: CSNK1-IN-1
Chemical Name: CSNK1-IN-1
CAS Number: 2468784-55-4
Molecular Formula: C₂₉H₂₆F₃N₅O₂
Molecular Weight: 533.54
Catalog: Research Areas Cancer
Create Date: 2023-01-15 17:21:44
Modify Date: 2025-08-25 19:42:45
CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].

Name	CSNK1-IN-1

Description	CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 21 μM (CSNK1A1 kinase)[1]
In Vitro	CSNK1-IN-1 对 CSNK1A1, CSNK1D 和 CSNK1A1 (高 ATP) 具有抑制活性，IC50 值分别为 21 μM, 29.7 μM 和 1.5 nM[1]。< br / >CSNK1-IN-1 对野生型 EGFR 激酶表现出低抑制作用，其 IC50 值为 >20 nM[1]。
References	[1]. Volker Schulze, et al. 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

Molecular Formula	C₂₉H₂₆F₃N₅O₂
Molecular Weight	533.54

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