CSNK1-IN-1

Names

[ Name ]:
CSNK1-IN-1

Biological Activity

[Description]:

CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 21 μM (CSNK1A1 kinase)[1]

[In Vitro]

CSNK1-IN-1 对 CSNK1A1, CSNK1D 和 CSNK1A1 (高 ATP) 具有抑制活性，IC50 值分别为 21 μM, 29.7 μM 和 1.5 nM[1]。< br / >CSNK1-IN-1 对野生型 EGFR 激酶表现出低抑制作用，其 IC50 值为 >20 nM[1]。

[References]

[1]. Volker Schulze, et al. 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₆F₃N₅O₂

[ Molecular Weight ]:
533.54

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.