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2468783-76-6

2468783-76-6 structure

2468783-76-6 structure

Name: CSNK1-IN-2
Chemical Name: CSNK1-IN-2
CAS Number: 2468783-76-6
Molecular Formula: C₂₈H₂₆FN₅O₂
Molecular Weight: 483.54
Catalog: Research Areas Cancer
Create Date: 2023-04-08 18:34:20
Modify Date: 2024-09-15 13:21:21
CSNK1-IN-2 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 2.52 μM. CSNK1-IN-2 can be used for the research of proliferative disorders[1].

Name	CSNK1-IN-2

Description	CSNK1-IN-2 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 2.52 μM. CSNK1-IN-2 can be used for the research of proliferative disorders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 2.52 μM (CSNK1A1 kinase)[1]
In Vitro	CSNK1-IN-2 (example 7) 对 CSNK1A1、CSNK1D 和 CSNK1A1 (高 ATP) 具有抑制活性，IC50 值分别为 2.52 μM、8.48 μM 和 107 μM[1]。< br / >CSNK1-IN-2 对野生型 EGFR 激酶具有抑制作用，其 IC50 值为 2.74 nM[1]。
References	[1]. Volker Schulze, et al. 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

Molecular Formula	C₂₈H₂₆FN₅O₂
Molecular Weight	483.54

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