920868-45-7
920868-45-7 structure
- Name: MASM7
- Chemical Name: MASM7
- CAS Number: 920868-45-7
- Molecular Formula: C22H23N5O2S2
- Molecular Weight: 453.58
- Catalog: Research Areas Others
- Create Date: 2022-10-18 17:31:02
- Modify Date: 2024-01-11 17:24:58
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MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins[1].
| Name | MASM7 |
|---|
| Description | MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins[1]. |
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| Related Catalog | |
| In Vitro | MASM7 increases Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 μM. MASM7 does not induce DNA damage in any of the cell lines. MASM7 does not decrease cellular viability over the course of 72 h. MASM7 does not induce caspase-3/7 activation in U2OS cells. MASM7 concentration responsively increases mitochondrial membrane potential in WT MEFs[1]. |
| References |
| Molecular Formula | C22H23N5O2S2 |
|---|---|
| Molecular Weight | 453.58 |