Propargylcholine (bromide)
Modify Date: 2024-01-12 11:51:08
Propargylcholine (bromide) structure
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Common Name | Propargylcholine (bromide) | ||
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| CAS Number | 111755-76-1 | Molecular Weight | 208.096 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H14BrNO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Propargylcholine (bromide)Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells[1][2]. |
| Name | Propargylcholine (bromide) |
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| Synonym | More Synonyms |
| Description | Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells[1][2]. |
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| Related Catalog | |
| In Vitro | Propargylcholine bromide (10, 50 µM; 24 h) 掺入 NIH 3T3细胞中，并以浓度依赖性方式显示强染色 (用 Alexa568 叠氮化物固定并染色)[1]。 Immunofluorescence[1] Cell Line: NIH 3T3 cells Concentration: 10, 50 µM Incubation Time: 24 h Result: Showed strong staining proportional in intensity to the concentration of added Propargylcholine bromide. |
| In Vivo | Propargylcholine bromide (P-Cho; 3.5-4.0 mg/kg; i.p; single daily for 6 days) 在恒河猴中给药后 1 周内有效掺入新合成的髓磷脂并持续存在超过 6 周[2]。 |
| References |
| Molecular Formula | C7H14BrNO |
|---|---|
| Molecular Weight | 208.096 |
| Exact Mass | 207.025864 |
| Propargylcholine (bromide) |
| 2-Propyn-1-aminium, N-(2-hydroxyethyl)-N,N-dimethyl-, bromide (1:1) |
| N-(2-Hydroxyethyl)-N,N-dimethyl-2-propyn-1-aminium bromide |