Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].
m-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fmoc-Lys(Pal-Glu-OtBu)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys(Pal-Glu-OtBu)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Amino-PEG24-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
DBCO-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
DBCO-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG1-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].
m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
E3 Ligase Ligand-Linker Conjugates 19 is a degron-linker. The PROTAC linker is bound lo at least one targeting ligand.
HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG1-CH2CO2H is a PROTAC linker, which refers to the alkyl/ether composition. Azido-PEG1-CH2CO2H can be used in the synthesis of PROTAC BRD4 Degrader-1[1].
BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-3-Hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
m-PEG4-CH2-alcohol is PEG-based based PROTAC linker can be used in the synthesis of PROTACs.