Thalidomide-O-PEG2-propargyl

Modify Date: 2024-04-05 14:43:12

Thalidomide-O-PEG2-propargyl Structure
Thalidomide-O-PEG2-propargyl structure
Common Name Thalidomide-O-PEG2-propargyl
CAS Number 2098487-52-4 Molecular Weight 400.38
Density N/A Boiling Point N/A
Molecular Formula C20H20N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-PEG2-propargyl


Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

 Names

Name Thalidomide-O-PEG2-propargyl

 Thalidomide-O-PEG2-propargyl Biological Activity

Description Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Related Catalog
References

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

 Chemical & Physical Properties

Molecular Formula C20H20N2O7
Molecular Weight 400.38
Storage condition -20°C