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126415-02-9

126415-02-9 structure
126415-02-9 structure
  • Name: m-PEG2-O-Ph-3-NH2
  • Chemical Name: 3-[2-(2-Methoxyethoxy)ethoxy]aniline
  • CAS Number: 126415-02-9
  • Molecular Formula: C11H17NO3
  • Molecular Weight: 211.258
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-06 06:56:09
  • Modify Date: 2024-01-05 18:14:55
  • m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-[2-(2-Methoxyethoxy)ethoxy]aniline
Synonyms Benzenamine, 3-[2-(2-methoxyethoxy)ethoxy]-
MFCD11652541
3-[2-(2-Methoxyethoxy)ethoxy]aniline
Description m-PEG2-O-Ph-3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 346.2±27.0 °C at 760 mmHg
Molecular Formula C11H17NO3
Molecular Weight 211.258
Flash Point 173.9±17.4 °C
Exact Mass 211.120850
LogP 0.14
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.521