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89635-82-5

89635-82-5 structure
89635-82-5 structure
  • Name: Propargyl-PEG3-methane
  • Chemical Name: 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]prop-1-yne
  • CAS Number: 89635-82-5
  • Molecular Formula: C10H18O4
  • Molecular Weight: 202.24800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-09-13 13:55:11
  • Modify Date: 2024-01-16 19:08:01
  • Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]prop-1-yne
Synonyms methoxytriethylenoxy propargyl ether
2,5,8,11-Tetraoxatetradec-13-yne
Description Propargyl-PEG3-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H18O4
Molecular Weight 202.24800
Exact Mass 202.12100
PSA 36.92000
LogP 0.31580