PROTAC EGFR degrader 8
Modify Date: 2025-10-15 10:48:16
PROTAC EGFR degrader 8 structure
|
Common Name | PROTAC EGFR degrader 8 | ||
|---|---|---|---|---|
| CAS Number | 2925923-46-0 | Molecular Weight | 796.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H46ClN11O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC EGFR degrader 8PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1]. |
| Name | PROTAC EGFR degrader 8 |
|---|
| Description | PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Liang, Apeng, et al. Compounds for EGFR protein degradation and uses thereof.Patent. CN116135852. |
| Molecular Formula | C40H46ClN11O5 |
|---|---|
| Molecular Weight | 796.32 |