2925923-46-0
2925923-46-0 structure
- Name: PROTAC EGFR degrader 8
- Chemical Name: PROTAC EGFR degrader 8
- CAS Number: 2925923-46-0
- Molecular Formula: C40H46ClN11O5
- Molecular Weight: 796.32
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2023-09-28 18:48:22
- Modify Date: 2024-04-07 08:58:27
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PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1].
| Name | PROTAC EGFR degrader 8 |
|---|
| Description | PROTAC EGFR degrader 8 (T-184) is a PROTAC EGFR degrader. PROTAC EGFR degrader 8 degrades EGFR in HCC827 cell with a DC50 of 15.56 nM. PROTAC EGFR degrader 8 inhibits H1975, PC-9, HCC827 cell growth with IC50s of 7.72 nM, 121.9 nM, 14.21 nM. PROTAC EGFR degrader 8 can be used for research of cancer, especially NSCLC[1]. |
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| Related Catalog | |
| References |
[1]. Liang, Apeng, et al. Compounds for EGFR protein degradation and uses thereof.Patent. CN116135852. |
| Molecular Formula | C40H46ClN11O5 |
|---|---|
| Molecular Weight | 796.32 |