1449390-11-7

1449390-11-7 structure

1449390-11-7 structure

Name: HS-PEG5-CH2CH2N3
Chemical Name: HS-PEG5-CH2CH2N3
CAS Number: 1449390-11-7
Molecular Formula: C₁₂H₂₅N₃O₅S
Molecular Weight: 323.41
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:06:33
Modify Date: 2024-01-31 00:47:49
HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	HS-PEG5-CH2CH2N3

Description	HS-PEG5-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₂₅N₃O₅S
Molecular Weight	323.41

Hazard Codes	Xi