Hydroxy-Amino-bis(PEG2-propargyl)

Modify Date: 2025-08-27 19:21:38

Hydroxy-Amino-bis(PEG2-propargyl) Structure
Hydroxy-Amino-bis(PEG2-propargyl) structure
 Common Name Hydroxy-Amino-bis(PEG2-propargyl)
CAS Number 2100306-77-0 Molecular Weight 313.39
Density N/A Boiling Point N/A
Molecular Formula C16H27NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-Amino-bis(PEG2-propargyl)


Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Hydroxy-Amino-bis(PEG2-propargyl)
Synonym More Synonyms

 Hydroxy-Amino-bis(PEG2-propargyl) Biological Activity

Description Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H27NO5
Molecular Weight 313.39

 Synonyms

MFCD30723249
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