1393330-34-1

1393330-34-1 structure

Name: Azido-PEG1-C2-acid
Chemical Name: Azido-PEG1-acid
CAS Number: 1393330-34-1
Molecular Formula: C₅H₉N₃O₃
Molecular Weight: 159.143
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-10-17 18:57:04
Modify Date: 2025-08-31 11:47:46
Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG1-acid
Synonyms	MFCD22574801 Propanoic acid, 3-(2-azidoethoxy)- 3-(2-Azidoethoxy)propanoic acid

Description	Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562