Methyl 1-Cbz-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Cbz-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1
Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
Benzyl-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].
Benzyl-PEG9-Ots is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Benzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(m-PEG4)-N'-(azide-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Acid-PEG6-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
t-Boc-Aminooxy-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pomalidomide-5-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].
Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker[1].
Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG12-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-Boc-N-bis(PEG3-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
MS-PEG10-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC KRAS G12C degrader-2 (compound 432) is a modulator of K-Ras protein hydrolysis. PROTAC KRAS G12C degrader-2 is a bifunctional compound, which contain on one end a cereblon inhibitor of apoptosis proteins (IAP) and on the other end a moiety which binds KRAS[1].
E3 ligase Ligand-Linker Conjugates 34 Hydrochloride incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 34 Hydrochloride can be used to design PROTAC degrader[1].
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs..
Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Tetrahydropyranyldiethyleneglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
HO-PEG21-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].