1872433-61-8

1872433-61-8 structure

1872433-61-8 structure

Name: 1,1,1-Trifluoroethyl-peg5-tos
Chemical Name: 1,1,1-Trifluoroethyl-PEG4-Tos
CAS Number: 1872433-61-8
Molecular Formula: C₁₇H₂₅F₃O₇S
Molecular Weight: 430.44
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:25:41
Modify Date: 2024-01-04 16:36:44
1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,1,1-Trifluoroethyl-PEG4-Tos
Synonyms	MFCD29079383

Description	1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₇H₂₅F₃O₇S
Molecular Weight	430.44