m-PEG4-phosphonic acid

Modify Date: 2024-01-12 12:47:54

m-PEG4-phosphonic acid Structure
m-PEG4-phosphonic acid structure
Common Name m-PEG4-phosphonic acid
CAS Number 1872433-62-9 Molecular Weight 272.23
Density N/A Boiling Point N/A
Molecular Formula C9H21O7P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-phosphonic acid


m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG4-phosphonic acid
Synonym More Synonyms

 m-PEG4-phosphonic acid Biological Activity

Description m-PEG4-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H21O7P
Molecular Weight 272.23

 Synonyms

MFCD29079386