Thalidomide-O-C8-Boc

Modify Date: 2024-01-09 20:56:57

Thalidomide-O-C8-Boc Structure
Thalidomide-O-C8-Boc structure
Common Name Thalidomide-O-C8-Boc
CAS Number 2225148-52-5 Molecular Weight 486.56
Density N/A Boiling Point N/A
Molecular Formula C26H34N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-O-C8-Boc


Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].

 Names

Name Thalidomide-O-C8-Boc

 Thalidomide-O-C8-Boc Biological Activity

Description Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].
Related Catalog
Target

Cereblon

References

[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.

 Chemical & Physical Properties

Molecular Formula C26H34N2O7
Molecular Weight 486.56
Storage condition -20°C